CONCENTRATIONS – compatibility is often concentration dependent
DILUENT– medication must be compatible with diluent
LINES AND LUMENS – peripheral or central, number of lumens in central line
HOW WILL THE MEDICATIONS COME INTO CONTACT – Y-site, admixture, syringe
ADMINISTRATION RATES – indicates duration of contact
CONTAINER – PVC, polyethylene, polyurethane, polyolefin
OTHER PARENTERAL MEDICATIONS/ FLUIDS – provides alternative compatibility options
pH – medications unlikely to be compatible if there is a large difference in pH
SAFETY – will administration change the rate of the medication already running. Is this safe/appropriate?
ALTERNATIVE – route of administration (eg rectal)
Palliative Care/Syringe Driver Compatibility
|If compatibility uncertain and concurrent administration unavoidable, alert prescriber and monitor for signs of physical incompatibility (precipitation, cloudiness, colour change) – the event of which requires cessation of the infusion.|
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