Skip to Main Content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

SA Pharmacy Medicines Information Service



CREATININE/UREA – pattern/percentage change. Creatinine does not necessarily need to be above the normal range for a significant change in renal function  

AGE, HEIGHT, WEIGHT – creatinine clearance decreases by ~10mL/min with every 10y of age. Anticipated maximum creatinine clearance for a 70y old will be 70mL/min

DIALYSIS –  what type, specific dialysis machine if known, timing of medications in relation to dialysis

CREATININE – ensure no hepato-renal syndrome/renal impairment if using medications which are renally cleared

THERAPEUTIC INDEX & DURATION OF USE – assists dose recommendations

NEPHROTOXICITY – hold/suspend any non-essential medications which could have caused nephrotoxicity

Specialised Resources



Societal Guidelines


Need help with these resources or your question? Contact Medicines Information


Something not working - report a problem with access.