CREATININE/UREA – pattern/percentage change. Creatinine does not necessarily need to be above the normal range for a significant change in renal function
AGE, HEIGHT, WEIGHT – creatinine clearance decreases by ~10mL/min with every 10y of age. Anticipated maximum creatinine clearance for a 70y old will be 70mL/min
DIALYSIS – what type, specific dialysis machine if known, timing of medications in relation to dialysis
CREATININE – ensure no hepato-renal syndrome/renal impairment if using medications which are renally cleared
THERAPEUTIC INDEX & DURATION OF USE – assists dose recommendations
NEPHROTOXICITY – hold/suspend any non-essential medications which could have caused nephrotoxicity
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